… risk factor for all chronic diseases since biological systems change with age. For this reason…
an antiaging effect by reducing inflammation and oxidative stress. SIRT2 mainly controls cell …

… to obtain spiropyrazolone analogue with outstanding biological activity, and … redox system
homeostasis by inducing the accumulation of intracellular ROS, which caused DNA damage …

… refers to a pathological process in which the redox state in cells is destroyed due to the … of
REDOX system. Studies have shown that oxidative stress is often unbalanced with the level of …

… aged brain, shows that aging is only a biological clue. The … a slow steady accumulation of
oxidative damage to macromolecules. … NADPH-dependent redox systems powered by glucose …

… Insulin resistance and oxidative stress are major pathogenic mechanisms leading to chronic
liver diseases … , could decrease oxidative stress and reduce liver damage in obese gerbils. …

… effects of oxidative stress are more prominent in advanced diabetes and include an imbalance
in systemic oxidative stress mechanisms, as well as increased penile protein oxidative …

… The complete oxidation of nutrients for biological energy supply is one of the most important
… the homeostasis is disturbed oxidative stress occurs. Upon oxidative stress, the free radicals …

… 英文摘要 Chapter 1: We briefly introduced biological thiols … ROS via redox cycling, leading
to oxidative stress to cells. In … system to decrease the ability of cells against oxidative stress. …

… Kainic acid is a neurotoxic agent that acts by binding and activating glutamate receptors in
the central nervous system to increase both oxidative stress and neuron damage; kainic acid …

… oxidationreduction cycle during turnover. Despite of the efficiency of these systems (SOD/CAT)
against ROS, oxidative stress … relevant in more-complex biological systems. The kinetic …